Todd DeSantis in

Todd DeSantis

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VP of Bioinformatics at Resilient Biotics
📍 San Francisco Bay Area, United States

Todd DeSantis is a VP of Bioinformatics & Data Science with over two decades of experience building data platforms for life science companies. He specializes in ontologies, knowledge graphs, and AI, and holds degrees from UC Santa Barbara and Cal Poly. Colleagues describe him as detail-oriented and versatile.

He is passionate about improving how large pharmaceutical companies manage their data, advocating for a data-centric approach to avoid the redundant, siloed systems that hinder scientific progress and AI leverage.

Unique fact: In recognition of his significant contributions to the field of microbiome research, a bacterial phylum was named "Desantisbacteria" in his honor.

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Experience
26 Years
Current Role
VP of Bioinformatics
Job Level
Senior
Location
San Francisco Bay Area, United States
Personality Overview

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Communication Style
Decision Approach
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Priorities

Topics Todd cares about

Ontologies & Knowledge Graphs
This is his core expertise. He builds ontologies and knowledge graphs that enable life science companies to trust their data and apply AI effectively.
AI in Drug Discovery
He focuses on making AI applications ready for drug discovery and has spoken at conferences about leveraging high-dimensional data for AI.
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Career

Work history

3-2023
VP of Bioinformatics
Resilient Biotics
2-2023
Co-Founder and Chief Data Officer
Genevive
1-2023
Data Management and Analysis Consultant
Self Employed
5-2010 - 7-2023
Co-Founder and VP of Informatics
Second Genome, Inc.
6-2006 - 4-2010
Software Developer
Lawrence Berkeley National Lab
In the press

Media appearances

Todd DeSantis, formerly of Second Genome, to join Resilient Biotics as Vice President of Bioinformatics. Featured in Resilient Biotics
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Todd DeSantis, Second Genome, Inc., Microbiome‑Host Relationship Discovery via Network Analysis and Machine Learning. Featured in Carnegie Science
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Education
MS
California Polytechnic State University-San Luis Obispo
BA
UC Santa Barbara
Social presence
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Behavioral profile

DISC profile (public)

DISC behavioral profile

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