Katherine High, MD

Energizer
DISC Type : I

Emeritus Medical Staff at Children's Hospital of Philadelphia

Haverford, Pennsylvania, United States

Overview

Katherine High is a pioneering gene therapy scientist and the CEO of RhyGaze. She co-founded Spark Therapeutics, where she led the development of the first FDA-approved gene therapy for a genetic disease. She earned her BA from Harvard University and her MD from the UNC School of Medicine.

Outside of her extensive scientific career, Katherine is an avid reader with a deep interest in the history of science and medicine. She has mentioned in interviews that she owns a farm, suggesting a connection to life beyond the laboratory and boardroom.

Katherine was the co-recipient of the inaugural $1 million Sanford Lorraine Cross Award for Medical Innovation for her groundbreaking work.

Personality Overview

Big Picture Person

Imaginative

Believer

They are naturally enthusiastic, so take their promise with a pinch of salt.  Unlike C or D types, they are vocal with their opinions but not so much with their questions. They are not always early adopters but can be pursuaded by leveraging strong relationships.

Topics They Care About

Gene Therapy Development
Her entire career has focused on advancing gene therapy from basic and translational research to successful clinical investigation and commercialization.
Translational Medicine
She specializes in bridging the gap between academic research and commercial application, having co-founded Spark Therapeutics and now leading RhyGaze.
Biotech Leadership
As a co-founder, president, CSO, and now CEO, she has extensive experience building and leading companies at the forefront of genetic medicine.

Media Appearances

Spark co-founder Katherine High leads RhyGaze. Featured in Bizwomen

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Dr. Katherine High Returns as CEO of RhyGaze. Featured in Instagram

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Katherine High, MD, Awarded Esteemed CHOP Gold Medal. Featured in Children's Hospital of Philadelphia (CHOP) Research

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Work History

12-2025
Emeritus Medical Staff at Children's Hospital of Philadelphia
12-2024
Chief Executive Officer at RhyGaze
LIfe Sciences Advisor at GV (Google Ventures)
Board Member at CRISPR Therapeutics
Board Member at Incyte

Education

Bachelor of Arts - BA from Harvard University
Doctor of Medicine - MD from UNC School of Medicine

More Information

Social Presence :

Prographics :

Exp : 1 Location : Haverford, Pennsylvania, United States Job Level : Leadership Designation : Emeritus Medical Staff at Children's Hospital of Philadelphia
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Insights For Selling To Katherine

During A Call Or A Meeting

DO's

  • Talk anecdotally about the customer experience that your product offers
  • Be friendly and entertaining in your conversation
  • Speak enthusiastically with energy, maintain a clear and confident tone

DONT's

  • Avoid overloading them with too much detail
  • Don’t push them to make a decision too fast, let them get comfortable first
  • Don’t assume a yes just because they have not said no

When Cold Calling

When Writing An Email

While Negotiating & Closing

    The secret to closing fast with Katherine is

  • Relationship and trust can be vital with them, sometimes more than anything else.
  • Will you ever get a clear answer from Katherine

  • They are unlikely to say no directly, you have to make that decision yourself.

Insights For Deal Planning

    How fast (or slow) will Katherine move?

  • They are not the fastest decision makers, their friendly approach can give false positive signals.
  • Can Katherine take some risk or not?

  • They can take certain risks that are unlikely to have personal consequences.

You And Katherine

Personality Compatibility


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