Carlos J. V. Simões in

Carlos J. V. Simões

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Senior Scientist Translational Research at VIB
📍 Leuven, Flemish Region, Belgium

Carlos J. V. Simões is a scientist-entrepreneur specializing in translating academic research into new therapies. As co-founder and CTO of BSIM Therapeutics, he leverages his expertise in computational drug discovery and molecular modeling to design treatments for amyloid diseases. He earned his Pharm. D and Ph. D. from the University of Coimbra and conducted research at the University of Leeds.

His professional focus is on developing novel drugs for neurodegenerative diseases, particularly transthyretin-mediated amyloidosis. He is passionate about using high-performance computing and biomolecular simulation to solve complex medical challenges. His work demonstrates a deep commitment to addressing unmet clinical needs through scientific innovation.

Interesting fact: Carlos is an inventor on two patents granted in the US and Europe for compounds designed to inhibit amyloid fibril formation.

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Experience
19 Years
Current Role
Senior Scientist Translational Research
Job Level
Leadership
Location
Leuven, Flemish Region, Belgium
Personality Overview

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Priorities

Topics Carlos cares about

Computational Drug Discovery
A core theme of his career, from his PhD work to his role as CTO at BSIM Therapeutics and current position at VIB, focusing on Computer-Aided Drug Discovery (CADD).
Amyloid Disease Therapeutics
His PhD, multiple publications, and two patents are centered on discovering and designing novel inhibitors and therapies for amyloid-related diseases like FAP.
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Career

Work history

6-2022
Senior Scientist Translational Research
VIB
1-2012
Chief Technology Officer
BSIM Therapeutics
1-2011 - 12-2011
Research Fellow
PRACE
9-2009 - 6-2011
Scientific coordinator of AMILOIDE
Ibercivis
10-2007 - 12-2010
Research scholar
Institute of Molecular and Cellular Biology
In the press

Media appearances

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Education
2006 - 2011
Doctor of Philosophy (PhD)
Universidade de Coimbra
2007 - 2010
Doctor of Philosophy (Ph.D.)
University of Leeds
Social presence
in
Behavioral profile

DISC profile (public)

DISC behavioral profile

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