Yupeng He in

Yupeng He

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Director, Bioinformatics at Guardant Health
📍 San Francisco Bay Area, United States

Yupeng He is the Director of Bioinformatics at Guardant Health, where he leads efforts in early cancer detection. A computational biologist with a PhD from UC San Diego, he specializes in applying machine learning to large-scale genomics and epigenomics data, a skill he has honed throughout his progressive roles within the company.

He demonstrates a strong commitment to continuous learning, extending beyond his technical expertise. His interest in business strategy is highlighted by his Micro-MBA certification and following publications like the Harvard Business Review. He also actively stays current with technological advancements by attending conferences on topics like Agentic AI.

Unique fact: Yupeng placed first out of ten teams in the 2016 bioCADDIE Dataset Retrieval Challenge.

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Experience
16 Years
Current Role
Director, Bioinformatics
Job Level
Mid-senior
Location
San Francisco Bay Area, United States
Personality Overview

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Decision Approach
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Priorities

Topics Yupeng cares about

Early Cancer Detection
His entire role at Guardant Health is dedicated to this challenge, and he is actively hiring computational scientists to detect tumor-derived DNA in blood.
Computational Biology
His background and numerous publications are centered on analyzing complex genomics and DNA methylation data to derive biological insights.
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Career

Work history

2-2025
Director, Bioinformatics
Guardant Health
4-2023 - 2-2025
Associate Director, Bioinformatics
Guardant Health
4-2022 - 4-2023
Sr. Manager, Bioinformatics
Guardant Health
10-2020 - 4-2022
Manager, Bioinformatics
Guardant Health
4-2019 - 10-2020
Senior Bioinformatics Scientist
Guardant Health
In the press

Media appearances

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Education
2011 - 2017
Doctor of Philosophy (PhD)
UC San Diego
2007 - 2011
B.S.
Shanghai Jiao Tong University
Social presence
in
Behavioral profile

DISC profile (public)

DISC behavioral profile

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